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Voltage-dependent deactivation of IKACh when it is activated by ACh.

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posted on 14.01.2022, 21:04 by Ana Laura López-Serrano, Rodrigo Zamora-Cárdenas, Iván A. Aréchiga-Figueroa, Pedro D. Salazar-Fajardo, Tania Ferrer, Javier Alamilla, José A. Sánchez-Chapula, Ricardo A. Navarro-Polanco, Eloy G. Moreno-Galindo

a) IKACh generated by 10 μM ACh at +30 (red trace) and -100 mV (black trace) to measure the time course of the deactivation process (b). The basal current level is indicated by the dashed lines in panel a. n = 7 myocytes. *, P = 0.01.