Volcano plot with the –log10 transformed unadjusted p-values versus the log fold change from the differential abundance analysis on the different taxonomic levels found in vaginal samples of healthy breeding bitches analyzed by Next Generation Sequencing.
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posted on 2025-04-28, 17:30 authored by Anna Sophia Leps, Eva-Maria Packeiser, Christina Schwens, Benjamin Stoelcker, Semir Doric, Martina Wirkner, Beate Walter, Axel Wehrend, Viktoria Kichmann, Klaus Jung, Sandra Goericke-PeschThe horizontal line marks the significance level, i.e., –log10(0.05). While a few features are significant according to the raw P-value, significance is lost after P-value adjustment.
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previous studies investigatingmade notable advancescanine vaginal bacteriafertility mostly reliedcanine vaginal microbiomebalanced vaginal microbiomecorrelate ngs datahealthy breeding bitchesvaginal samplefertility datasuccessful breedingbreeding examinationngs revealedngs analysisngs ),diverse microbiomexlink ">statistical analysisroutine prerecent yearsprovide evidenceoften thoughtlitter sizelarger differencesindependent methodsimportant prerequisitehealthy littersgeneration sequencingfirst studyblood samplebecome popularbecame pregnantaerobic culturing
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