Violin plots showing the log2 fold change of 28 differentially expressed genes after metformin use.
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posted on 2020-08-11, 17:32 authored by Monta Briviba, Laura Ansone, Ivars Silamikelis, Vita Rovite, Ilze Elbere, Laila Silamikele, Ineta Kalnina, Davids Fridmanis, Jelizaveta Sokolovska, Ilze Konrade, Valdis Pirags, Janis KlovinsEach dot represents the log2 fold change for a particular gene of one study subject. The shape of the plot represents the distribution of the data obtained using kernel density estimate and Scott's rule for bandwidth selection.
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type 2 diabetesmultiple health conditionsmitochondrial respiratory compleximmune responses (<cholesterol homeostasis (<based molecular discriminationinduced differential expression>( cyp1b1 div >< p>, cancer developmentexpression levelsvivo stab1 slc46a1 irs2 cd163 cd14 ccr2 wide applicationtmem176b )three monthstherapeutic responsetherapeutic efficacysystemic effectsignificant upregulationreliable biomarkersprovide evidencenaïve volunteerslrp1 )lowering effectlongitudinal bloodhighly variablehigh variabilityglycemic responsefc 0factors relatedexplaining 13delta hba1cbiguanide agent6 mmol56 genes
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