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VE-cadherin is reexpressed during delamination stages.

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posted on 14.01.2022, 18:40 by Renee Wei-Yan Chow, Hajime Fukui, Wei Xuan Chan, Kok Soon Justin Tan, Stéphane Roth, Anne-Laure Duchemin, Nadia Messaddeq, Hiroyuki Nakajima, Fei Liu, Nathalie Faggianelli-Conrozier, Andrey S. Klymchenko, Yap Choon Hwai, Naoki Mochizuki, Julien Vermot

Images of Tg(ve-cad:ve-cad-TS) embryos at 48 to 50, 60, 65, and 80 hpf. Red arrow points to strong VE-cadherin signal between luminal cells at the future delamination site. Cyan arrow points to low VE-cadherin signal between the inner layer of the leaflet and the endocardial cells comprising the AVC wall. Orange arrows point to interfaces where VE-cadherin is up-regulated after being down-regulated following cell migration. Scale bar: 10 μm. AVC, atrioventricular canal; hpf, hours postfertilization.