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pntd.0008458.s003.ai (1.61 MB)

Topological predictions of kinetoplastid aquaglyceroporins.

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posted on 2020-07-09, 17:54 authored by Juan F. Quintana, Juan Bueren-Calabuig, Fabio Zuccotto, Harry P. de Koning, David Horn, Mark C. Field

TbAQP1, TbAQP2, TbAQP3, a field-isolated chimera AQP2/3 (40AT) and a single TMD mutant (AQP2TMD4) are predicted to have both N- and C-termini facing the cytoplasm and six TMD. Predictions were generated using TMHMM (v2.0) [64].

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    PLOS Neglected Tropical Diseases

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    TbAQP 2 stabilityERcytoplasmic-oriented lysine residuesdrug resistanceubiquitin conjugation sitesTbAQP 2TbAQP 2 mediates pentamidine transl...flagellar pocket membraneTbAQP 2 mediates pentamidine sensit...

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