TUNEL staining of SARS-CoV-2 infected k18hACE2 mice hippocampus.
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posted on 2024-10-30, 17:40 authored by Motoki Imai, Fumitaka Kawakami, Takayuki Uematsu, Toshihide Matsumoto, Rei Kawashima, Yoshifumi Kurosaki, Shun Tamaki, Shotaro Maehana, Takafumi Ichikawa, Hideaki Hanaki, Hidero Kitazato, Makoto KuboTUNEL positive cells in hippocamps of brain sections from k18hACE2-mice uninfected or infected with 5×104 PFU 7 days after administration. Bar is 100 μm.
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xlink "> covidx (&# 947ventral tegmental regionventral tegmental areausing brain tissueinfectious disease causedgsk3 &# 946decreased serotonin synthesisimmunohistochemical analysis revealedtryptophan hydroxylase 22 spike proteinphosphorylated tau protein18hace2 mice infectedphosphorylated tauinfected miceimmunohistochemical staining2 propagation2 infectionunderlying mechanismterm mentalsitu hybridizationresults suggestrecovering patientspositive neuronspositive cellsphysical distressmemory impairmentintranasal administrationincreased accumulationhistone h2acauses long
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