Fig 6.tif (3.53 MB)
TGF-β signalling in the renal tubulointerstitium.
figure
posted on 2016-03-03, 08:28 authored by Ines Marek, Till Lichtneger, Nada Cordasic, Karl F. Hilgers, Gudrun Volkert, Fabian Fahlbusch, Wolfgang Rascher, Andrea Hartner, Carlos Menendez-CastroA, Counting of p-SMAD2/3-positive nuclei in tubulointerstitial cells of wild type and Itga8-/- mice after induction of unilateral ureter obstruction (UUO). B, Exemplary photomicrographs of renal sections show staining for p-SMAD2/3. C, Western blot analysis comparing p-SMAD protein levels in both genotypes after UUO. Itga8+/+, wild type mice; Itga8-/-, Itga8-deficient mice. Data are means±SEM. # p<0.05 UUO versus control (co), * p<0.05 Itga8+/+ versus Itga8-/-.
