TFAB002s did not exhibit binding affinity towards CHO-K1 cells.
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posted on 2024-09-25, 17:24 authored by Qinghong Li, Kunming Zhang, Yao Yu, Zeng Yu, Jingyi Xu, Wenyan Shen, Lin Zhang, Aidong Qu, Hongyuan LiangFACS was performed to assess TFAB002s’ binding ability towards antigen-negative parent cell line CHO-K1.
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moderate binding affinityexpress varying levelsencompass various subtypesbinding fragment 002dependent bispecific fabdependent bispecific antibodiesselectively depleting cd20thereby triggering targetviable treatment optiontumor cell lysispositive b cellsdiv >< pspecifically target cd20optimal targetthereby warrantingconstructing fabtherapeutic antibodiesnovel cd20vivo vitro tfab002 ),tandem antigenresults underscorenovel nonnormal tissuesmalignant bheterogeneous groupexpressing bcytokine releaseclinical evaluationcell lymphomacell activation
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