Sperm and testis parameters and histology.
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posted on 2022-06-28, 17:33 authored by Lena Arévalo, Gina Esther Merges, Simon Schneider, Franka Enow Oben, Isabelle Sophie Neumann, Hubert Schorle(A) Bar plots showing data for relative testes mass, mature sperm count, percentage of viable mature sperm (eosin-nigrosin assay) and percentage of motile mature sperm in Prm2+/Δc and Prm2-/Δc mice compared to wildtype. (B) PAS staining of testis and epididymal sections of Prm2+/Δc, Prm2-/Δc and WT males. Scale bar = 50μm (200μm for left column).
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precursor protein consistingmale mouse fertilityhighly conserved nprotect paternal chromatinpaternal chromatin packagingsperm chromatin packagingproper chromatin condensationcalled mature prm2sperm chromatin condensationxlink "> protaminesmice generated mice lackingcomplete dna fragmentationmp2 ), interactstermed cleaved prm2chromatin condensationmediates chromatinunique spermprm2 ),transition proteinsterminal domainstill expressedspecific ratiospecific proteinsprotamine exchangekey aspectincomplete histoneepididymal transitcp2 ),consecutively trimmedcomplex crosstalkcarboxyterminal part
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