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Single carbon metabolite levels differ between C57BL/6Mthfr-/- and C57BL/6 mice.

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posted on 2018-01-12, 18:32 authored by Kenneth R. Eyring, Brent S. Pedersen, Kenneth N. Maclean, Sally P. Stabler, Ivana V. Yang, David A. Schwartz

(A) Single Carbon metabolism pathway. C57BL/6Mthfr-/- mice demonstrate altered levels of single carbon metabolites (homocysteine, HCYS; cystathionine, CYSTAT; dimethylglycine, DMG; methylglycine, MG; methionine, METH; cysteine, CYS; glycine, GLY; alpha aminobutyrate, ABUT; serine, SER) in (B) serum and (C) whole lung tissue compared to C57BL/6 mice (C57BL/6 black bars; C57Bl/6Mthfr-/- white bars, * p-value <0.05, *** p-value <0.001).

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