pone.0232849.g003.tif (502.63 kB)
Sequence conservation/variation and evolutionary importance of HLA I α-3 domain positions.
figure
posted on 2020-05-18, 17:32 authored by Onur Serçinoğlu, Pemra Ozbek(A) Sequence logo of the HLA I α-3 domain (residues 181–261). Polar, neutral, basic, acidic and hydrophobic amino acids are colored green, purple, blue, red, and black, respectively. (B) real-value Evolutionary Trace (rvET) scores of α-3 domain positions. Low rvET scores indicate high evolutionary importance, and vice versa.
History
Usage metrics
Categories
Keywords
protein interactionsfrustration perspective ClassHLA binding groovepMHC homology modelsKiller-cell Immunglobulin-like ReceptorsTCRfrustration analysisPLCbinding modeKIR-HLA interactionT-cell ReceptorsMajor Histocompatibility Complexpolymorphic proteinallelic diversityNatural Killer10000 allelesNKantigenic peptidesHLA helicesfrustration profilesfrustration patchescytotoxic T-cellsHLA peptide-binding groovePeptide Loading ComplexHuman Leukocyte AntigenSequence-structure-function relationships1436 HLAinteraction sitespeptide sequence space
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC