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Schematic representation of methylglyoxal pathway in Salmonella.

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posted on 2023-06-02, 18:05 authored by Sashi Kant, Lin Liu, Andres Vazquez-Torres

GLC, Glucose; FBP, Fructose 1,6 bis phosphate; DHAP, Dihydroxyacetone phosphate; G-3P, Glyceraldehyde 3-phosphate; PEP, Phosphoenolpyruvate; PYR, Pyruvate.

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    Keywords

    phagocyte nadph oxidaseperiplasmic superoxide dismutasesoffshoot metabolic adaptationmetabolic flexibility associatedinnate host responsehydroperoxidases detoxify superoxidebalance glucose utilizationmethylglyoxal pathway enablesmethylglyoxal pathway consumesconsuming methylglyoxal pathwayaerobic respiratory outputsglutathione reducing powerglutathione also helpsexperiencing oxidative stressmethylglyoxal pathwayoxidative stressrespiratory bursttaken togethertake advantagesubstantial proportionsalmonella report hereinphagocytic cellshydrogen peroxidefunctionally activatefollowing exposureenzymatic activitycurrently unknownantimicrobial actions

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