Fig 4.tif (2.46 MB)
Scanning electron microscopy of the tegument of S. mansoni adult worms.
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posted on 2017-09-12, 17:33 authored by Enyara R. Morais, Katia C. Oliveira, Renato G. de Paula, Alice M. M. Ornelas, Érika B. C. Moreira, Fernanda Rafacho Badoco, Lizandra G. Magalhães, Sergio Verjovski-Almeida, Vanderlei Rodrigues(A, x600) Normal morphology of adult worm tegument. (B, x1200) and (C, x3000) magnification of normal morphology of S. mansoni tegument showing the large number of tubercles (tu) and spines (sp). (D, x5000) Magnification of normal morphology of S. mansoni tegument showing spines (sp). (E, x600) Morphology of S. mansoni tegument after treatment with 50 μM MG-132 for 24 h. (F, x1200) Magnification showing tegumental changes in treated male adult worms: peeling (p), swelling (s), outbreak (o). (G, x3000) and (H, x5000) Magnification showing peeling (p) and bubbles (b) in the tegument promoted by MG-132.
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Schistosoma mansoni parasitesScanning electron microscopypartner cullin -3 ubiquitin ligase genespotassium channel activitiesubiquitin-like NEDD 8IAPIPAMG -132Bax pro-apoptotic geneapoptosis inhibitor genesgene expression modulatorparasite Schistosoma mansoni Proteasomeintracellular protein turnover19 S chaperones assembly20 S proteasome maturationgenes encoding proteinsproteasome inhibitor MG -132mansoni adult wormsIngenuity Pathway AnalysisBRE26 S proteasome genesintegral membrane componentpotassium ion bindingmicrotubule motor activitygene interaction networkMG -132.
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