Scanning electron microscopy of the tegument of S. mansoni adult worms.

(A, x600) Normal morphology of adult worm tegument. (B, x1200) and (C, x3000) magnification of normal morphology of S. mansoni tegument showing the large number of tubercles (tu) and spines (sp). (D, x5000) Magnification of normal morphology of S. mansoni tegument showing spines (sp). (E, x600) Morphology of S. mansoni tegument after treatment with 50 μM MG-132 for 24 h. (F, x1200) Magnification showing tegumental changes in treated male adult worms: peeling (p), swelling (s), outbreak (o). (G, x3000) and (H, x5000) Magnification showing peeling (p) and bubbles (b) in the tegument promoted by MG-132.