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posted on 2024-05-09, 17:29 authored by Assia Samri, Antonio Carlos Bandeira, Luana Leandro Gois, Carlos Gustavo Regis Silva, Alice Rousseau, Aurelien Corneau, Nadine Tarantino, Christopher Maucourant, Gabriel Andrade Nonato Queiroz, Vincent Vieillard, Hans Yssel, Gubio Soares Campos, Silvia Sardi, Brigitte Autran, Maria Fernanda Rios GrassiAnalysis of clustering of CD4+ (A) and CD8+ (B) T cells by Volcano plot analysis from ZIKV-infected patients (ZIKV+) (N = 16) collected during the acute phase of the disease illness (P1) or during convalescent phase (P2) and from healthy donors (HD) (N = 10). Clusters that differ significantly between ZIKV+ and HD are indicated by green circles.
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sup >+mild clinical symptomslimited acute illnesszikv antigen resultsnonstructural zikv proteinsexpress elevated levelsacute zikv infectionprominent among cd4including transitional memoryfunctional activation characteristicscells exhibit phenotypicbrazil infected patients exhibitedxlink "> circulating4 ), comparedxlink ">increased levelstemra ),tem ),infected patientsinfected cellsviremic phaseresolve withinquantified usingimmune responseshealthy donorsfirst epidemicexpressing cd45raeffector memorycomprehensive analysiscirculating cd4central rolecell subsetscell subsetcell responsesapproximately 30
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