(A) CYP2D6.1, (B) CYP2D6.2, (C) CYP2D6.10, (D) CYP2D6.14A, (E) CYP2D6.62. The simulation of CYP2D6.51 did not converge. For the mutant CYP2D6, RMSF values (red) were compared with those of the wild type (gray).