Representative photomicrographs of liver sections from 3 wild boar naturally infected with hepatitis E virus.

Fig 2A: liver with absence of association of the HEV antigen inside the lymphoplasmacytic aggregates (Immunohistochemistry (IHC) with the avidin-biotin-peroxidase complex (ABC) method counterstained with hematoxylin). Fig 2B: hepatitis E virus (HEV) immunolabeling in the cytoplasm of the Kupffer cells (arrowhead) and the sinusoidal endothelial cells (arrow) (IHC with ABC method). Fig 2C: HEV immunostaining of a light lymphoplasmacytic infiltrate (arrowhead) (IHC with ABC method). Fig 2D: liver showing slight labeling for HEV antigen in the hepatic parenchyma, which is appreciable in the Kupffer cells (inset) (IHC with ABC method).