posted on 2024-12-02, 18:44authored byYibo Wu, Guangjing Mu, Fang Li, Yanfei Sun, Xiaoying Lin, Xuemeng Liu, Zhimin Zhao, Mingzhi Han, Donghai Wang, Bin Huang, Xingang Li
(A) ZNF503-AS2 expression is upregulated in GBM in the TCGA database. (B) ROC curve analysis of ZNF503-AS2 predicts GBM in the TCGA database. (C-E) ZNF503-AS2 expression is upregulated in GBM (C), LGG (D) and all glioma (E) in TCGA combined with the GTEx database. (F) ZNF503-AS2 was significantly positively correlated with the enrichment scores of the MES and CL subtypes and significantly negatively correlated with the enrichment scores of the NE and PN subtypes. (G, H) ZNF503-AS2 was positively correlated with the MES subtype markers CD44 (G) and CHI3L1 (H). (I) Heatmap of MES signature genes. NS, not statistically significant; * P < 0.05; ** P < 0.01; *** P < 0.001.