Fig 2.TIF (1.3 MB)
Physical map and conceptual origin for different unc-29 duplication events.
figure
posted on 2016-07-14, 11:49 authored by Thomas B. Duguet, Claude L. Charvet, Sean G. Forrester, Claudia M. Wever, Joseph A. Dent, Cedric Neveu, Robin N. BeechPanels A) to F) correspond to different paralogous families. An idealized history for each family is indicated to the left. A physical map for different species is shown to the right, based on genome data from WormBase ParaSite (WBPS2) or the Sanger Center haemonchus_V1 genome build from 2012. Arrows indicate extent of the gene from start to stop codon, where differences in length occur in introns. Direction of transcription is indicated for each gene and maps are drawn to scale, as indicated.
History
Usage metrics
Categories
Keywords
gene copiesreceptor assemblyanthelmintic drug targetsreceptors reconstitutedphenotype rescueCaenorhabditis eleganscodon substitution rate analysisacetylcholine receptorssubunits co-expressedRecent DuplicationXenopus oocytesnematodeacetylcholine receptor subunit genesFunctional Divergencenovel drug targetssubunit duplicationfast-synaptic transmissionclade Vgenome dataHaemonchus contortusunc -29acetylcholine receptor subunitacid positions25 speciesreceptor composition changesubunit compositionParasitic Nematode Levamisole-Sensitive Acetylcholine Receptors Helminth parasitesgene duplicationsubunit assemblypentameric levamisole-sensitive acetylcholine receptor50 helminth genome initiative
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC