Partial genomic sequences of lin-15B with mutations identified in the jy76 and jy86 alleles.
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posted on 2025-04-07, 17:27 authored by Eillen Tecle, Paaramitha Warushavithana, Samuel Li, Michael J. Blanchard, Crystal B. Chhan, Theresa Bui, Ryan S. Underwood, Malina A. Bakowski, Emily R. Troemel, Vladimir Lažetić(A, B) Wild-type and mutated nucleotides in jy76 (A) and jy86 (B) are shown on the positive strand, with mutated nucleotides highlighted in red boxes (uppercase letters).Surrounding sequences, including 500 nucleotides upstream and downstream, are displayed in gray boxes (lowercase letters).
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unrestrained immune responsessumoylation histone modifiersrepressing immune responsesdiv >< pconserved thap domaincause negative impacts4 histone methyltransferasetranscriptional immune responserobust transcriptional responsesintracellular pathogen responsenatural intracellular pathogenscaenorhabditis elegans intracellular pathogenselegans transcriptional repressor15b related factorsincreased resistanceforward geneticsfindings suggestdamaging inflammationconstitutive expressionbroad rangealso involved
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