Nonlinear associations between MET and biological age based on restricted cubic spline models.
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posted on 2025-05-07, 20:03 authored by Guang Chen, Shichen Zhou, Yunqing Xun, Tung Leong Fong, Guoyi Tang, Jingyi Wang, Hongzheng Li, Xiangjun Yin, Jialiang Gao, Guanghui Zhu, Ying Wu, Jinlin Li, Ya Xuan Sun, Yige Li, Jiayan Zhou, Yibin FengThe cubic spline models also adjusted for gender, race, BMI, sleep disorder, smoking, alcohol intake, and history of cancer. The solid blue line represents the smooth curve fit between dependent and independent variables. The grew bands represent the 95% confidence interval from the fit. (A) PhenoAge; (B) ENABL Age.
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minutes per weekcubic spline model5 82112007 8211promoting healthy ageinghealthy ageing managementaccelerated ageing comparedseven survey cyclesnutrition examination surveyworld health organizationsignificant risk factorgeneralized linear regression600 met minutes259 met minutespromoting physical exercisephysical activity levelsdelayed biological ageinghispanic black individuals1 8211enabl age algorithmsdaily caffeine intakeappropriate met levelsweekly physical exercisexlink "> ageingmd ]: 22 phenoage yearsenabl age ).physical exercisebiological ageingxlink ">weekly exerciseenabl agecaffeine intakemet levelsageing purposesurvey datanational healthlinear relationshipshigher riskhigher levelscaffeine consumption05 ).met levelmet increaseyear delaytest correlationsstudy aimedstronger effectsshaped associationsectional analysisresults underscorerelated diseasesmean differencejoint associationincome populationsfindings highlightdiminishing benefitsconfounding factorsassessed usinganalyzed data739 participants
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