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Nonlinear associations between MET and biological age based on restricted cubic spline models.

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posted on 2025-05-07, 20:03 authored by Guang Chen, Shichen Zhou, Yunqing Xun, Tung Leong Fong, Guoyi Tang, Jingyi Wang, Hongzheng Li, Xiangjun Yin, Jialiang Gao, Guanghui Zhu, Ying Wu, Jinlin Li, Ya Xuan Sun, Yige Li, Jiayan Zhou, Yibin Feng

The cubic spline models also adjusted for gender, race, BMI, sleep disorder, smoking, alcohol intake, and history of cancer. The solid blue line represents the smooth curve fit between dependent and independent variables. The grew bands represent the 95% confidence interval from the fit. (A) PhenoAge; (B) ENABL Age.

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