Neutralization associated germline allele from RLk17 was not present in other Z1800M Env immunized RM.

The germline VH allele associated with the development of neutralizing antibodies in RLk17 was present in 4 other RMs, all immunized with the R66M Env containing vaccines. In animals that did not harbor this germline allele, the allele with the highest identity is shown. One animal that received the Z1800M trimer vaccine, RYf17, had a highly similar germline but did not develop neutralizing antibodies.

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