Microvessel density of VLN flaps after IR injury.
figure
posted on 2020-10-06, 17:27 authored by Florian S. Frueh, Bijan Jelvani, Claudia Scheuer, Christina Körbel, Bong-Sung Kim, Pietro Giovanoli, Nicole Lindenblatt, Yves Harder, Emmanuel Ampofo, Michael D. Menger, Matthias W. Laschke<p><b>A-D</b> Immunohistochemical sections of control (<b>A</b> and <b>B</b>), IR-45 (<b>C</b>) and IR-120 (<b>D</b>) VLN flaps illustrating CD31<sup>+</sup> microvessels (arrowheads) in lymph nodes. <b>B</b> (insert of <b>A</b>) CD31<sup>+</sup> paracortical microvessels (arrowheads). Dashed arrows in <b>D</b> = local hemorrhages. <b>E</b> Lymph node microvessel density (mm<sup>-2</sup>). Mean ± SEM, n = 7–8, **<i>P</i> < 0.001. <b>F-H</b> Immunohistochemical sections of control (<b>F</b>), IR-45 (<b>G</b>) and IR-120 (<b>H</b>) VLN flaps illustrating CD31<sup>+</sup> microvessels (arrowheads) in the perinodal adipose tissue. <b>I</b> Adipose tissue microvessel density (mm<sup>-2</sup>). Mean ± SEM, n = 7–8, *<i>P</i> < 0.05. Scale bars: <b>A, C</b> and <b>D</b> = 250 μm, <b>B</b> = 40 μm, <b>F-H</b> = 60 μm. VLN = vascularized lymph node.</p>
