Metabolic analysis of cellular metabolism in steatotic and non-steatotic livers during perfusion.

Ratio of metabolite concentration fold change at each hour of perfusion compared to pre-perfusion concentration shown for (a) tricyclic acid cycle, (b) glycolysis, and (c) pentose phosphate pathway. Steatotic livers demonstrate decreased flux through each metabolic pathway. ** indicates P≤0.05, * indicates 0.05