Fig 3.TIF (1.38 MB)
Kaplan-Meier curves of progression-free survival (PFS) for 62Cu-ATSM PET (a) and 18F-FDG PET (b) in patients with HNC.
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posted on 2016-05-17, 21:18 authored by Tetsuya Tsujikawa, Satoko Asahi, Myungmi Oh, Yoshitaka Sato, Norihiko Narita, Akira Makino, Tetsuya Mori, Yasushi Kiyono, Tatsuro Tsuchida, Hirohiko Kimura, Shigeharu Fujieda, Hidehiko OkazawaTwo groups of high (dotted lines) and low (solid lines) tracer accumulation were determined by each cut-off value of the tumor-to-muscle ratios (TMRATSM and TMRFDG). TMRATSM, one of the intensity-based redox parameters, showed a significant difference in PFS between two groups (p = 0.03), whereas TMRFDG, one of the intensity-based metabolic parameters, did not (p = 0.15). The three-year PFS rate was 74% for patients with lower accumulation tumors (TMRATSM ≤ 3.2) and 29% for those with over-reductive tumors (TMRATSM > 3.2).
