Kaplan-Meier curves for clinical endpoints in patients with low, normal and high platelet (PLT) count.
(A) Overall survival. Patients with high PLT (red line) had significantly higher mortality rate during follow up. (B) Myocardial infarction free survival. Patients with high PLT had significantly higher rates of myocardial infarction during follow up. (C) Transient ischemic attack/ cerebrovascular accident (TIA/CVA) free survival. Patients with low PLT (blue line) compared to patients with normal PLT had significantly lower rates of TIA/CVA. (D) Bleeding free survival. No significant difference in bleeding episodes was seen between the 3 groups. A tendency for higher bleeding rate was seen in patients with low compared to normal PLT. (E) Combined-1 free survival. The rate of the combined-1 outcome that included mortality, MI, TIA/CVA, systemic emboli and bleeding was significantly higher among patients with high PLT.