pcbi.1011472.g007.tif (444.56 kB)
Interpretations of the relations between tumor and normal tissues inferred by TranNet.
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posted on 2023-09-18, 17:31 authored by Bayarbaatar Amgalan, Chi-Ping Day, Teresa M. PrzytyckaTranNet predictors (light blue) in normal tissue predict environment-related changes in tumor (light grey) (A). Cancer-specific functional enrichment of predictor genes (light blue) and inferred environmentally modulated changes in tumor (light gray) (B).
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results allow usseveral cancer typescancer genome atlaspotential stromal facilitatorsfirst computational methodutilizes gene expressiongene expression profilesrelated immune responseadjacent control samplesmatched control samplesmany predictors identifiedgene expressionmatched controlcontrol samplescancer studiespredictors identifiedpotential regulatorspathways relatedimmune processescomputational approachtumor samplesxlink ">valuable resourceunderstanding rolestissue remodellingtcga ).prognostic biomarkersnormal crossinferred predictorsidentify predictorshealthy tissuesgrowing awarenessgenes associated
