Increased frequency of NK and T cells expressing Ki67 in the ART + SIV RhmAbs + N-803 group.

Frequency of NK cells (A), CD8+ T cells (B), and CD4+ T cells (C) expressing intracellular Ki67 measured by whole blood flow cytometry. Frequencies were compared at baseline (day 0) and day 4 after receipt of ART + SIVRhmAbs + N-803. Individual data points are plotted with mean and SD shown. Statistical analysis was performed using a paired Student’s t-test. (D-F) Frequency of peripheral blood NK cells (D), CD8+ T cells (E), and CD4+ T cells (F) expressing intracellular Ki67 were compared across groups in the first week after ART +/- SIV RhmAbs +/- N-803 administration. Individual data points are plotted with mean and SD shown. Statistical analysis was performed using the non-parametric Kruskal-Wallis test with multiple comparisons to assess for differences across groups. ns = not significant; p > 0.05.