Histology.

Monocyte/macrophage staining (F4/80 positive cells, upper panels) revealed minor subcortical infiltrates in areas of small tubular atrophy after 35min IRI. Prolonged IRI caused severe persistent macrophage infiltration in both strains. Sv-mice had more severe infiltrates compared to B6-mice. Inflammatory cells accumulated in areas of tubular atrophy. Similar results were seen with infiltrating T-lymphocytes (CD3 positive cells, lower panels) with enhanced infiltration after 45min IRI. Here no differences between Sv- and B6-mice were detected (200 fold magnification). ** = p<0.01; ### = p<0.001 vs. Sv-mice.