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Histograms illustrating the expression of 3 genes encoding proteins known to be aberrant in different NDDs.

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posted on 2017-06-19, 17:31 authored by Cynthia L. Bethea, Kevin Mueller, Arubala P. Reddy, Steven G. Kohama, Henryk F. Urbanski

ADAM10 and SCNA mRNAs significantly increased with E–treatment, whereas PSEN1 mRNA significantly decreased with E-treatment in the chow-fed monkeys. The effect of E observed in the chow-fed monkeys was lost in the WSD-fed monkeys. In addition, transcript abundance was decreased by an order of magnitude for ADAM10 and PSEN1 in the WSD- compared to chow-fed monkeys. * Bonferroni posthoc p<0.001.

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