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Hemorrhage enhances the CRP and C3 responses and the early corticosterone response to radiation in the serum, but not the late corticosterone or Flt-3 ligand response.

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posted on 2017-09-21, 17:39 authored by Juliann G. Kiang, Joan T. Smith, Marsha N. Anderson, Thomas B. Elliott, Paridhi Gupta, Nagaraja S. Balakathiresan, Radha K. Maheshwari, Barbara Knollmann-Ritschel

Mice received 8.75 Gy γ-photon radiation. Blood was collected at several time points after RI and CI from the surviving mice (N = 6 per group at each time point). Corticosterone (A), CRP (B), C3 (C), and Flt-3 ligand (D) in serum were measured. All values are means±SEM. *p<0.05 vs. sham; ^p<0.05 vs. Sham: free of any injury; RI. Hemo: hemorrhage; RI: radiation injury; CI: RI+Hemo.

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