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GTTs and ITTs in Ocn–/–mice.

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posted on 28.05.2020, 17:25 by Takeshi Moriishi, Ryosuke Ozasa, Takuya Ishimoto, Takayoshi Nakano, Tomoka Hasegawa, Toshihiro Miyazaki, Wenguang Liu, Ryo Fukuyama, Yuying Wang, Hisato Komori, Xin Qin, Norio Amizuka, Toshihisa Komori

(A) GTT by glucose (2 g/kg body weight) injection. Glucose levels in male mice (wt: n = 9, Ocn–/–: n = 12) at 5 months of age fed a normal diet. (B and C) GTT by glucose (1 g/kg body weight) injection. Glucose (B) and insulin (C) levels in male mice at 9 months of age fed a normal diet. wt: n = 9, Ocn–/–: n = 7. (D and E) GTT by glucose (2 g/kg body weight) injection. Glucose (D) and insulin (E) levels in male mice (wt: n = 8, Ocn–/–: n = 12) at 6 months of age fed a high-fat diet for 1 month. (F) ITT. Glucose levels in male mice (wt: n = 20, Ocn–/–: n = 12) at 4 months of age fed a normal diet. (G) ITT. Glucose levels in male mice (wt: n = 7, Ocn–/–: n = 12) at 8 months of age fed a high-fat diet for 3 months.

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