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Faster SIV viral load decay in the ART + SIV RhmAbs group and opposite effect with the addition of N-803.

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posted on 2025-01-10, 20:20 authored by Omotayo Farinre, Tzoalli Anaya, Alexis C. King, Kedan Endrias, Anne H. Hébert, Alison L. Hill, Sherrie Jean, Jennifer S. Wood, Stephanie Ehnert, Shan Liang, Gregory M. Laird, Rosemarie D. Mason, Mario Roederer, Jeffrey T. Safrit, Maud Mavigner, Ann Chahroudi

(A), Viral load values and individual fit trajectories for each animal after ART initiation are shown, with dashed lines indicating the lower limit of detection. (B), Simulated viral load decay trajectories by treatment group. Group mean trajectories show differences in the first and second phase decay rates. The trajectories for the ART only control and the ART + SIV RhmAbs treatment groups overlap after the first phase decay since there were no inferred effects of the SIV RhmAbs on the second phase decay rate. Dashed lines were used to indicate the overlap between the ART only group and the ART + SIV RhmAbs group.

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