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Expression of granzymes A, B and K by each lymphocyte subtype in patients with typhoid fever and controls.

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posted on 2017-07-27, 18:13 authored by Hanna K. de Jong, Maria Isabel Garcia-Laorden, Arie J. Hoogendijk, Christopher M. Parry, Rapeephan R. Maude, Arjen M. Dondorp, Mohammed Abul Faiz, Tom van der Poll, Willem Joost Wiersinga

Percentage of lymphocyte population expressing each granzyme (A–D) and MFI of the intracellular expression of each granzyme in the lymphocyte populations (E–H). n = 36 controls and 8 patients. MFI values are expressed with Log10 scale. Significance determined via Mann-Whitney U tests. Medians are shown. Analysis was done by flow cytometry. MFI: median fluorescence intensity; NK cells: CD3CD56+. *P<0.05, **P<0.01, ***P<0.001.

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