Evolutionary conservation of mammalian PEG3 proteins.

The exon structure of mouse Peg3 is presented with boxes indicating individual exons. The conservation level of each exon at the amino acid sequence level was calculated with Clustal Omega or Cobalt using the 10 representative PEG3 sequences, which were further summarized with a scheme involving boxes with different colors. The sequence of Exon9 was further divided into protein subdomains, including 12 zinc finger motifs and two proline-rich motifs (P1 and P2).