pone.0226123.g003.tif (421.73 kB)
Evaluation of degrees of order of spatial distribution of rhodopsin (Rh) dimers.
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posted on 2020-02-07, 18:28 authored by Yukito Kaneshige, Fumio Hayashi, Kenichi Morigaki, Yasushi Tanimoto, Hayato Yamashita, Masashi Fujii, Akinori AwazuAverages of 〈S(t)〉t over ten simulations, 〈S(t)〉, for each model with a different Rh dimer as indicated. Error bars indicate standard deviations. The “Initial” values were obtained for ten initial conditions, for which the configurations of H1/H8 dimers and lipids were random. The 〈S(t)〉t for each model of dimer indicates the time for the average degree of row structure by the Rh-dimers, S(t), ranging between 180 and 200 μs.
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row structureraftophilic regionsparticle populationsdisk membranespalmitoyl moietiesrod-photoreceptor cellsdisk membrane modelRh moleculeform dimerorder structureRh exhibits raftophilicityraftophilic lipidsphototransduction efficiencyphototransduction cascadeG protein-coupled receptorsingle-photon regimedisk membraneform rowsRh-dimer raftophilicityrow structuresdynamics simulationphotopigment protein rhodopsinlipid raftoligomer formationGPCRRh dimersnano-sized lipid raft domains actdynamics simulations
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