Effect of gugulipid on liver weight and histology and alanine transferase (ALT) level in male C57BL/6 mice.
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posted on 2017-09-14, 17:37 authored by Andrea Leiva, Susana Contreras-Duarte, Ludwig Amigo, Esteban Sepúlveda, Mauricio Boric, Verónica Quiñones, Dolores Busso, Attilio Rigotti(A) Liver weight, (B) hepatic histology, and (C) plasma ALT level in control and gugulipid-treated mice. Arrows in (B) indicate enlarged hepatocytes with cytoplasmic tumefaction and vacuolization. Two independent experimental sets were used; n = 6 in each set. Values represent mean ± SD. *P<0.05.
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scavenger receptor class B typealanine aminotransferase levelsplasma lipoprotein cholesterolgugulipidfarnesoid X receptorapolipoprotein E knockout miceatherosclerosicholesterol homeostasisGugulipid causes hypercholesterolemiaHDL metabolismHDL cholesterol levelsKOischemic heart diseaseSR-B 1 knockouthepatic SR-BI contentmodel
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