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Effect of SARS-CoV-2 infection on neuronal death-related molecules in k18hACE2 mice ventral tegmental area.

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posted on 2024-10-30, 17:40 authored by Motoki Imai, Fumitaka Kawakami, Takayuki Uematsu, Toshihide Matsumoto, Rei Kawashima, Yoshifumi Kurosaki, Shun Tamaki, Shotaro Maehana, Takafumi Ichikawa, Hideaki Hanaki, Hidero Kitazato, Makoto Kubo

γ-H2AX in the VTA of brain sections from k18hACE2 mice uninfected or infected with 5 × 104 PFU 6 days after administration. Bar is 100 μm. Western blot analysis of (B) γ-H2AX tissue lysates of the VTA from the brains of k18hACE2 mice uninfected or infected with 5×104 PFU 7 days after administration. The intensity of the bands corresponding to γ-H2AX was normalized to that of β-Actin. The data are representative of 6 mice per group, *P < 0.05, **P < 0.01.

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