ECTV infection does not trigger phenotypic maturation and inhibits LPS-induced maturation of GM-BM.

Mock-, uvi-ECTV- or ECTV-infected GM-BM were left untreated or were treated with LPS for 24 h. Representative histograms showing the major histocompatibility complex (MHC) (A) or co-stimulatory (B) molecules expression on GM-BM. Numbers represent the MFI value and/or the percentage of positive cells for a given marker. Graphs show mean ± SD of MFI and/or percentage for indicated marker from at least three independent experiments (paired Student’s t-test; ^*P< 0.05, ^**P< 0.01). Statistical comparisons were between mock- or uvi-ECTV-treated DCs and ECTV-exposed DCs and between LPS- or uvi-ECTV+LPS-treated DCs and ECTV + LPS-exposed DCs. IsCon–isotype control.