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Differential Methylation Analysis comparing ACC to normal adrenal.
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posted on 2016-03-10, 09:20 authored by Christophe R. Legendre, Michael J. Demeure, Timothy G. Whitsett, Gerald C. Gooden, Kimberly J. Bussey, Sungwon Jung, Tembe Waibhav, Seungchan Kim, Bodour SalhiaA) Box plot demonstrating overall lower median β value methylation levels for 1291 differentially methylated probes. B) Box plots showing β values of 1291 differentially methylated loci for each individual sample (6 normal and 18 ACC samples).
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Infinium HumanMethylation 450 BeadChip Arraytumor suppressorsPathway Implicationsdiscretization methodtumor typegenomic analysesTPtumor suppressor MARCKSAdrenocortical Cancer ContextAdrenocortical carcinomasACC tumors.ResultsThis correlation analysisACC.ConclusionsDNA methylationtreatment options.ObjectiveUnderstandingsurvival rateWNT18 ACC tumorsIGFDNA methylation levelsAberrant Global MethylationACC pathogenesiscorrelation approach
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