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DCE-MRI-Derived Parameters in Evaluating Abraxane-Induced Early Vascular Response and the Effectiveness of Its Synergistic Interaction with Cisplatin - Fig 4
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posted on 2016-09-15, 17:49 authored by Xilin Sun, Lili Yang, Xuefeng Yan, Yingying Sun, Dongliang Zhao, Yang Ji, Kai Wang, Xiaoyuan Chen, Baozhong Shen(A) Representative Kep parametric maps of female athymic nude mice bearing orthotopic MDA-MB-435 tumors on days 0 and 3 after different treatments were initiated. Decreased Kep values were observed on day 3 in both A and A-P groups. (B) Quantitative DCE-MRI region-of-interest analysis of Kep values. **, P < 0.01; ***, P < 0.001.
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cisplatinK transKi 67 histology datamonitoring Abraxane treatment outcomesK epAbraxane-mediated permeability variationsAbraxane therapyPBSA-PSMADynamic contrast enhanced-magnetic resonance imagingMDA-MB -435 tumor miceintegrin-specific PET tracer 18 F-FPPRGD 2K ep valuesday 3. Immunohistological stainingDCE-MRItumor vasculature
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