pone.0228559.g005.tif (737.63 kB)
Concentrations of neurotransmitters in the brain tissues of different groups of mice.
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posted on 2020-02-11, 18:27 authored by Xunwei Wu, Jun Huang, Cong Shen, Yeling Liu, Shengjie He, Junquan Sun, Bolan YuWT-CON: wild-type control, WT-OVX: wild-type ovariectomy, KO-CON: Nrf2−/− control, KO-OVX: Nrf2−/− ovariectomy. (a) Concentrations of 5-hydroxytryptamine (5-HT) in the brain tissues of different groups of mice at postoperative week 9. (b) Dopamine (DA) concentrations in the brain tissues of different groups of mice at postoperative week 9. Results are shown as mean ± SEM. *P < 0.05 analyzed by One-way ANOVA with Bonferroni's Multiple comparison test.
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menopausal women increasesNrf 2 deletion5- HT levelsT-CHOHDLKO control miceLDLNuclear factor E 2-related factor 2blood GLU levelpostoperative week 9.NRF 2 deficiency increases obesity susceptibilityWT control miceestrogen levelmetabolismmouse menopausal modelNrf 2 deficiencybodyweightantioxidant defense deficiencyDAoxidative stress sensorTGKO ovariectomized mice9. Neurotransmitter dopamineovariectomized menopausal model
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