Comprehensive correlation analysis between the RNA-Seq and Affymetrix expression array platforms.
figure
posted on 2013-09-26, 01:53 authored by Fernando J. Rossello, Richard W. Tothill, Kara Britt, Kieren D. Marini, Jeanette Falzon, David M. Thomas, Craig D. Peacock, Luigi Marchionni, Jason Li, Samara Bennett, Erwin Tantoso, Tracey Brown, Philip Chan, Luciano G. Martelotto, D. Neil Watkins(A) Comparison of gene expression detected by RNA-Seq and Affymetrix expression array platforms for identical SCLC samples (mean, n = 3, P<0.01). (B) Comparison of the gene expression between SCLC primary tumours [34] (Y axis, mean, n = 15) and primary xenografts (X axis, mean, n = 3) (P<0.01). (C) Comparison of gene expression detected by Affymetrix array of micro-dissected human cancer stroma [19] (Y axis, mean, n = 28) and mouse-specific RNA-Seq expression data in the SCLC xenograft models (X axis, mean, n = 3) (P<0.01).
