pone.0270572.g003.tif (1.27 MB)
Download fileComparison of the solution structure of PRC1-DD and the corresponding segments in crystal structure.
figure
posted on 05.08.2022, 20:04 authored by Fei Tan, Jin Xu(a) Superimposition of ribbon representation of the PRC1-DD lowest-energy solution structure and crystal structure; H1 and H2 of the solution structure are colored yellow and orange, respectively, while H1 and H2 of the crystal structure are colored in cyan and blue, respectively; C and N tags signify C- and N-terminal ends, respectively. (c) Enlargement of the dotted box in (a). Figures were plotted using MATLAB, while the alignment was performed using CHIMERA.
History
Usage metrics
Read the peer-reviewed publication
Categories
Keywords
hydrophobic core packingdeuterium exchange experiments>- helix h2proteins called microtubulecycle dependent proteinsn terminal residuesalso generated mutantsdiv >< pconformation prc1 adoptedhigh resolution threeprc1 </ presolution solution structureassociated proteinsn terminusalso differentalpha </prc1 ’prc1 callswhole proteinused hydrogenthermal stabilityspindle midbodysolution structuressolution structureresults suggestplacing hurdlesphysiological significancenmr spectroscopyincomplete sidechainshuman mapfunction relationshipsdistinguishing memberdimerization domaindimensional structurebind microtubules