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Combination Index (CI) values for actual experimental datapoints.

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posted on 2021-01-07, 23:11 authored by Dina Moustafa, Maha R. Abd Elwahed, Hanaa H. Elsaid, Jeffrey D. Parvin

A constant-ratio drug combinations 1:1 of olaparib:CHK1 I was analyzed in all cells tested. When analyzing the proliferation of EMI1-depleted cells versus control siRNA transfected cells, the CI values for all concentrations tested were lower than 1, suggestive of a synergistic effect between the two drugs under these conditions.

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