Cartoon representations of wildtype IgG Fc, monomeric Fc and fusion proteins.
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posted on 2016-08-01, 17:38 authored by Lu Shan, Magali Colazet, Kim L. Rosenthal, Xiang-Qing Yu, Jared S. Bee, Andrew Ferguson, Melissa M. Damschroder, Herren Wu, William F. Dall’Acqua, Ping Tsui, Vaheh Oganesyan(A) Cartoons of Fc homodimer in IgG and in a bivalent Fc fusion protein, as well as a one-arm mAb and a monovalent Fc fusion, supported by heterodimeric Fc (as shown) or tethered Fc. (B) Cartoons of a monomeric Fc, along with Fab- and scFv- fusion proteins with a monomeric Fc.
