COG/KOG classification and KEGG pathway analysis.

(A-C) COG/KOG functional classification of the DEPs analysis. (A) pre-treatment/post-treatment; (B) under-treatment/post-treatment; (C) pre-treatment/under-treatment. Herein, the X and Y axes in COG analysis results refer to the classification of COG and the frequency number of COG/KOG, respectively; (D-F) KEGG enrichment analysis of the DEPs. (D) pre-treatment/post-treatment, (E) under-treatment/post-treatment, (F) pre-treatment/under-treatment. The size of the circle represents the number of DEPs in the mapping pathway, and the larger circle represents more DEPs. The color of the circle represents the p-value. As the color deepens, the p-value decreases.