CNN effects on B16 melanoma are not due to osmotic stress.
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posted on 2017-10-18, 17:55 authored by Shuji Nakamura, Toshio Kunikata, Yohsuke Matsumoto, Toshiharu Hanaya, Akira Harashima, Tomoyuki Nishimoto, Shimpei UshioB16 cells were treated with 50 mM CNN and isotonic samples of mannose (50 mM), isomaltose (50 mM), NaCl (25 mM), and glycine (50 mM) for 4 days. Levels of melanin and total protein were determined, as shown in A and B, respectively. **, p<0.01; statistically significant differences were analyzed by one-way ANOVA and Dunnett’s post hoc testing. Data are representative results of at least two independent experiments.
