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CD8+ T cell memory potential retained in Nur77-GFP+ OT-I.

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posted on 2022-06-21, 17:41 authored by Lindsey A. Shallberg, Anthony T. Phan, David A. Christian, Joseph A. Perry, Breanne E. Haskins, Daniel P. Beiting, Tajie H. Harris, Anita A. Koshy, Christopher A. Hunter

(A) OT-I from spleen of T. gondii-OVA 10 dpi (N = 4 mice). (B-C) OT-I from spleen of T. gondii-OVA 10 dpi were sorted by Nur77-GFP expression and transferred into naive mice. Mice were sacrificed 14 days post transfer (N = 4 mice). (D) Identification of OT-I from mice receiving either Nur77-GFP+ or Nur77-GFP- OT-I. (E-F) Characterization of OT-I from recipient mice. P values based on Students T-test with Bonferroni-Dunn correction for multiple comparisons **p<0.01, ***p<0.001; error bars indicate SD.

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