Adjusted odds ratios of SARS-CoV-2 positivity according to prescription drug use.

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posted on 2024-11-27, 18:40 authored by Aleksander Eiken, Sofie Bliddal, Marie Villumsen, Kasper K. Iversen, Henning Bundgaard, Rasmus B. Hasselbach, Jonas H. Kristensen, Pernille B. Nielsen, Mia M. Pries-Heje, Andreas D. Knudsen, Kamille Fogh, Jakob B. Norsk, Ove Andersen, Thea K. Fischer, Ram B. Dessau, Sisse R. Ostrowski, Christian Torp-Pedersen, Sisse B. Ditlev, Mikkel Gybel-Brask, Erik Sørensen, Lene H. Harritshøj, Fredrik Folke, Thomas Benfield, Frederik N. Engsig, Henrik E. Poulsen, Henrik Ullum, Ulla Feldt-Rasmussen, Susanne D. Nielsen, Jørgen Rungby

Adjusted odds ratios for having a positive SARS-CoV-2 test (PCR or ELISA) according to use of prescription drugs (yes/no) in the six months before date of infection, compared to controls matched on sex, age and chronic diseases. Prescription drug categories are based on the Anatomical Therapeutic Chemical Classification System as defined by the World Health Organization (codes are listed in parenthesis). The analysis was adjusted for body mass index (BMI) (<18.5, 18,5–25,25–30, >30 kg/m², missing), smoking (yes, no, former smoker, missing), alcohol intake (0, 0–7, 7–15, >15 units per week, missing), educational level (none or short, middle, long, missing), patient contact (none, partly, full time, missing), and region of employment (Capital Region or Region Zealand). *) Indicates SARS-CoV-2 positive fraction in percent of drug users and no-drug users, respectively. Abbreviations: Adj., adjusted. OR, odds ratio. PCR, polymerase chain reaction. SARS-CoV-2, Severe Acute Respiratory Syndrome Coronavirus-2.