AAS distributions for static and dynamic protein conformations.

Cumulative distribution functions (CDFs) of static protein structure without glycosylation (A), with GlycoSHIELD glycosylation (B), and CDFs of fully dynamic simulated protein structure without glycosylation (C) and with glycosylation (D). CDFs of the scores are shown for all residues (black); surface residues (blue); mutation sites at the surface of Omicron BA.1 (green), Omicron BA.5 (purple), and earlier variants (orange). The KS statistic is the maximum vertical gap between the respective CDFs, as indicated by red arrows.

(EPS)